• AutoTL;DR@lemmings.worldB
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    4 months ago

    This is the best summary I could come up with:


    Dosenbach, an associate professor of neurology at Washington University School of Medicine in St. Louis, had been given a high dose of psilocybin, the active substance in magic mushrooms, by his colleagues.

    The results, which appear in the journal Nature, suggest that psychedelic drugs work by disrupting certain brain networks, especially one that helps people form a sense of space, time and self.

    The disruptions in brain networks appear to be “where the plasticity effects of psychedelics are coming from,” says Dr. Joshua Siegel, a researcher at Washington University and the study’s lead author.

    Dosenbach and other participants were randomly assigned to receive either a stimulant or 25 milligrams of psilocybin, a dose high enough to cause hallucinations.

    The loss of synchrony was greatest in a brainwide group of neurons called the default mode network, which is active when the brain is daydreaming or otherwise not focused on the outside world.

    The study hints at how psychedelic drugs could be incorporated into the treatment of people with addiction, depression or post-traumatic stress.


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