“There was a time when he was a rebellious and unpromoted captain of the First Foundation’s commercial empire, when it would have been himself rather than Channis who would have taken prompt and daring action such as that. Was the Mule right? Was his controlled mind so concerned with obedience as to lose initiative? He felt a thickening despondency drive him down into a strange lassitude.”
Second Foundation by Isaac Asimov p33