There’s one single thing in the entire universe that I’m absolutely certain of - something nothing could ever change my mind about: the fact that it feels like something to be. That there’s qualia, subjective experience. I could be a simulation, a brain in a vat, or something else entirely - but it’s undeniable that it is like something to be whatever “me” is. Everything else is up for debate.

Now, sure - there are things it would take a lot to convince me otherwise about, but I’m also not married to my ideas. I don’t attach my identity to them. I’ve been wrong before, and I’m almost certainly wrong about plenty of things even now. I don’t reject ideas just because I don’t like them. There are uncomfortable truths in this world, and not believing them doesn’t make them untrue. Even politically, it would be statistically absurd to think one side is right about everything and the other side is wrong about everything. It’s a mix. The challenge is figuring out where you are mistaken.

As for the examples you mentioned - homosexuality and transsexuality are human-made labels, ways to describe patterns we see. But like all labels, they’re rough generalizations. The differences between individuals even within these groups are vast - so much so that it starts to put the usefulness of the label itself into question. Personally, I’m just me. Tomorrow I’ll be a slightly different version of me. I don’t even fully identify with who I was yesterday - let alone some rigid label that society wants to stick on me.