Israeli Prime Minister Benjamin Netanyahu left for Washington on Monday, leaving behind a brutal war to make a politically precarious speech before the U.S. Congress at a time of great uncertainty following Joe Biden’s withdrawal from the presidential race.

With efforts ongoing to bring about a cease-fire between Israel and Hamas, rising concerns about the war spreading to Lebanon and Yemen, and the U.S. in the midst of a dizzying election campaign, Netanyahu’s speech has the potential to cause disarray on both sides of the ocean.

The risks only increased with Biden’s decision Sunday to drop out of the race for president, especially since the choice of a replacement Democratic nominee — and the potential next American leader — are still up in the air.

“In this time of war and uncertainty, it’s important that Israel’s enemies know that America and Israel stand together,” he said, adding that he will meet Biden during his trip and thank him for his support for Israel.